Collagen reorganization at the tumor-stromal interface facilitates local invasion
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چکیده
منابع مشابه
Collagen reorganization at the tumor-stromal interface facilitates local invasion
BACKGROUND Stromal-epithelial interactions are of particular significance in breast tissue as misregulation of these interactions can promote tumorigenesis and invasion. Moreover, collagen-dense breast tissue increases the risk of breast carcinoma, although the relationship between collagen density and tumorigenesis is not well understood. As little is known about epithelial-stromal interaction...
متن کاملAuthor's Response to Reviews Collagen Reorganization at the Tumor-stromal Interface Facilitates Local Invasion Ms# 5901362451064822
We are re-submitting our revised manuscript entitled "Collagen reorganization at the tumor-stromal interface facilitates local invasion" by Paolo P. Provenzano, Kevin W. Eliceiri, Jay M. Campbell, David R. Inman, John G. White, Patricia J. Keely for possible publication as an article in BMC Cancer. We have carefully addressed each of the reviewers' concerns and submit a point-by-point response ...
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Stromal changes are the key factors for provision of nutrition and growth to any tumor and also they act as a barrier for spread of the tumor. There are limited histochemical studies in the literature on methods to detect, quantify and analyze the collagen in the invasive tumor front (ITF) of oral squamous cell carcinoma (OSCC). Aim: 1) To analyze the nature of collagen (thickness, hue, density...
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ژورنال
عنوان ژورنال: BMC Medicine
سال: 2006
ISSN: 1741-7015
DOI: 10.1186/1741-7015-4-38